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信号通路 血管生成 凋亡 自噬 细胞周期 表观遗传 细胞骨架
DNA损伤和修复 内分泌与激素 G蛋白偶联受体 免疫与炎症 JAK/STAT信号通路 MAPK信号通路 离子通道
代谢 微生物学 神经科学 NF-κB信号通路 氧化还原 PI3K/Akt/mTOR信号通路 蛋白酶体
干细胞 蛋白酪氨酸激酶 泛素化 PROTAC 其他
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Fragment片段库 高溶解性片段库 精选片段库 高溶解性多官能团片段化合物库 高溶解性卤化片段化合物库 药物片段库 Mini片段亲电杂环化合物库 高溶解性微型片段化合物库
类药性化合物库 多样性核心库Part2 多样性核心库Part1 药物靶点库 多样性核心预制库 Golden骨架库 Mini骨架库 化合物库深度定制
TargetMol Compound Library
天然产物库 高通量筛选天然产物库 特色天然产物库 天然产物衍生物库 虚拟筛选天然产物库
结构类型 萜类 类固醇 类黄酮 醌类 香豆素 木脂素 多糖和糖苷
苯丙烷 生物碱 酚类 其他
植物来源 列当科 水龙骨科 南洋杉科 报春花科 海金沙科 商陆科 买麻藤科
萝藦科 肉豆蔻科 鸭跖草科 交让木科 三白草科 海桐花科 五味子科 红厚壳科
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计算机辅助药物设计 虚拟筛选 分子对接 反向找靶 分子动力学模拟
基于靶点筛选实体化合物活性筛选 分子结合&互作检测 酶学靶点活性检测 核受体靶点活性检测 GPCR靶点活性检测
基于表型筛选实体化合物活性筛选 细胞增殖检测 细胞周期检测 细胞凋亡检测 药代动力学研究
药物设计和结构优化 化合物定制合成 分子砌块 网络药理学平台 软件平台
细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白
CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白 酶 •   氧化还原酶 •   转移酶
病毒蛋白 •   冠状病毒蛋白 •   流感病毒蛋白 荧光蛋白 其他蛋白

搜索结果

Search Results for " interleukin 7 receptor "
Targets Recommended: IRAK

2

抑制剂 & 化合物

3

天然产物

27

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T5354 IRAK4-IN-7

CA-4948

 IRAK Immunology/Inflammation; NF-κB
IRAK4-IN-7 (CA-4948) 是白介素 1 受体相关激酶 4 (IRAK4) 的选择性抑制剂，口服有活性。它可用于研究癌症以及炎症疾病。
T4140 IRAK4-IN-1

IRAK Immunology/Inflammation; NF-κB
IRAK4-IN-1 是白细胞介素-1 受体相关激酶 4 抑制剂(IC50:7 nM)。

化合物

IRAK4-IN-7
Cat.No: T5354
Synonym: CA-4948
Target: IRAK
IRAK4-IN-1
Cat.No: T4140
Synonym:
Target: IRAK
Cat. No. Product Name Target Signaling Pathways
T2S0843 Negletein

黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

 IL Receptor; TNF; NOS; Interleukin Apoptosis; Immunology/Inflammation
Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。
T7786 Tryptanthrin

DNA gyrase DNA Damage/DNA Repair
Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。 它能够降低大鼠胸膜炎模型中的 LTB4 水平，并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。
TN1291 7,3',4'-Tri-O-methylluteolin

5-Hydroxy-3',4',7-trimethoxyflavone,木犀草素-7,3',4'-三甲醚

 TNF; COX; Interleukin Apoptosis; Immunology/Inflammation; Neuroscience
7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) 是来自草药马鞭草科的一种类黄酮，具有抗炎，解热，镇咳，抗糖尿病、抗癌和抗黑素生成特性。它以浓度依赖方式明显抑制促炎细胞因子，可显著降低在转录水平的诱导型一氧化氮合酶和环加氧酶-2 的 mRNA 表达。

天然产物

Negletein
Cat.No: T2S0843
Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether
Target: IL Receptor, TNF, NOS, Interleukin
Tryptanthrin
Cat.No: T7786
Synonym:
Target: DNA gyrase
7,3',4'-Tri-O-methylluteolin
Cat.No: TN1291
Synonym: 5-Hydroxy-3',4',7-trimethoxyflavone,木犀草素-7,3',4'-三甲醚
Target: TNF, COX, Interleukin
Species：
Human (20)
Mouse (3)
Cynomolgus (2)
Rat (2)
Expression System：
HEK293 Cells (25)
Baculovirus Insect Cells (1)
E. coli (1)
Tag：
C-His (5)
C-hFc (5)
C-His-Avi (4)
C-hFc-6xHis (2)
His (2)
His, Avi (2)
Tag Free (2)
C-6xHis (1)
C-hhFc (1)
hFc (1)
Cat. No. Product Name Species Expression System
TMPY-00635 IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)

IL7R α/CD127,interleukin 7

Cynomolgus HEK293 Cells
IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is Q38IC7.
TMPY-01209 IL-7R alpha/CD127 Protein, Human, Recombinant (His)

IL7RA,ILRA,CD127,CDW127,IL-7<...

 Human HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
TMPY-01446 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)

IL-18Rbeta,CD218b,IL-18R β/IL-18RAP,IL-18Rβ,ACPL,IL-18R-beta...

 Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is O95256-1.
TMPY-03154 IL-7R alpha/CD127 Protein, Rat, Recombinant (mFc)

IL7R α/CD127,interleukin 7

Rat HEK293 Cells
IL-7R alpha/CD127 Protein, Rat, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 51.4 kDa and the accession number is D4A3X8.
TMPY-03730 IL-7R alpha/CD127 Protein, Rat, Recombinant (His)

interleukin 7 receptor,IL7

Rat HEK293 Cells
IL-7R alpha/CD127 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is A6KGJ9.
TMPY-01367 IL-7R alpha/CD127 Protein, Mouse, Recombinant (His)

IL7R α/CD127,interleukin 7

Mouse HEK293 Cells
IL-7R alpha/CD127 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P16872.
TMPJ-00285 IL-7R alpha/CD127 Protein, Human, Recombinant (hFc & His)

CD127,IL-7R-alpha,IL-7R-α,Int...

 Human HEK293 Cells
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Human, Recombinant (hFc & His) is ...
TMPJ-00344 IL-18RAP Protein, Human, Recombinant (hFc & His)

IL-1R accessory protein-like,Interleukin-18 rec...

 Human HEK293 Cells
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
TMPJ-00284 IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)

Interleukin-7 receptor subunit al...

 Mouse HEK293 Cells
Interleukin 7 Receptor alpha (IL-7Rα), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7Rα is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7Rα is important for the generation of appropriate immune responses. IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc) is expres...
TMPY-05377 IL-7R alpha/CD127 Protein, Human, Recombinant (hFc)

ILRA,interleukin 7 receptor,IL

Human HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is P16871-1.
TMPY-06580 IL-7R alpha/CD127 Protein, Human, Recombinant (His & Avi), Biotinylated

IL7R α/CD127,ILRA,CD127,IL-7<...

 Human HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.14 kDa and the accession number is P16871-1.
TMPY-06316 IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated

IL-18Rbeta,IL-18R β/IL-18RAP,IL-1R7,IL18RB,IL-18RAc...

 Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 67.04 kDa and the accession number is NP_003844.1.
TMPY-06312 IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated

ACPL,CDw218b,IL-18RAcP,IL-18R-β,IL-1R-7,IL-1RAcPL,C...

 Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.76 kDa and the accession number is NP_003844.1.
TMPY-01200 IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)

IL-1R-7,IL-1R7,interleukin 18

Human HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.2 kDa and the accession number is O95256-1.
TMPJ-00059 IL-7 Protein, Human, Recombinant (His)

Interleukin-7,IL7,白细胞介素,IL-7<...

 Human HEK293 Cells
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-spe...
TMPJ-00042 TSLP Protein, Human, Recombinant

TSLP,Thymic stromal lymphopoietin

 Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...
TMPK-01331 TSLPR Protein, Cynomolgus, Recombinant (His)

CRL2,CRLF2,IL-XR,CRLF2Y,p2RY8/CRLF2 fusion,TSLPR,TSLP re...

 Cynomolgus HEK293 Cells
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
TMPJ-00239 IL-2RG Protein, Mouse, Recombinant (aa 25-263, hFc)

Il2rg,Interleukin 2 receptor, gamma chain,...

 Mouse HEK293 Cells
The Interleukin-2 receptor gamma chain (IL-2 Rγ, CD132) of the high affinity functional mouse IL-2 receptor complex is a member the hematopoietin receptor family. It is expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. Common IL2 receptor-γ Chain is required for IL-2 receptor signaling. Besides IL-2, the Common IL2 receptor-γ chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15....
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)

FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FGFBR,HBGFR,CEK,HRTFDS,fibrob...

 Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7.
TMPY-02246 HB-EGF Protein, Human, Recombinant

DTSF,DTR,HEGFL,heparin-binding EGF-like growth factor,DTS

 Human Baculovirus Insect Cells
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells but not endothelial cells. HBEGF activates two EGF receptor subtypes, HER1 and HER4, and binds to cell surface HSPG. The transmembrane form of...
TMPK-00828 Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)

PEMT,Episialin,Mucin1,PUM,KL-6,MUC-1,Mucin-1,H23AG,PEM,CA 15...

 Human HEK293 Cells
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers.
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)

CD331,FGFR-1,FLT-2,BFGFR,N-sam,FGFR1 β (IIIc),bFGF-R-1

 Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb...
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-1,CD331,FGFR-1

 Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ...
TMPK-01371 IGFBP-7 Protein, Human, Recombinant (hFc)

RAMSVPS,TAF,IGFBPRP1,AGM,IBP7,MAC25,IGFBP-7

Human HEK293 Cells
IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Human, Recombinant (hFc) is expres...
TMPK-00395 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

FGF R1a,FGFR1 α,FGFR1 alpha,FGFR1 α (IIIc)

 Human HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
TMPK-00393 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)

FGFR1 α,FGFR1 alpha,FGF R1a,FGFR1 α (IIIc)

 Human HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)

KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,CD331,BFGFR,HBGFR,FLT-2,FGFB...

 Human HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7.

重组蛋白

IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-00635
Species: Cynomolgus
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His)
Cat.No: TMPY-01209
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His)
Cat.No: TMPY-01446
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Rat, Recombinant (mFc)
Cat.No: TMPY-03154
Species: Rat
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03730
Species: Rat
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01367
Species: Mouse
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00285
Species: Human
Expression System: HEK293 Cells
IL-18RAP Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00344
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00284
Species: Mouse
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05377
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06580
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06316
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06312
Species: Human
Expression System: HEK293 Cells
IL-18R beta/IL-18RAP Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01200
Species: Human
Expression System: HEK293 Cells
IL-7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00059
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant
Cat.No: TMPJ-00042
Species: Human
Expression System: E. coli
TSLPR Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01331
Species: Cynomolgus
Expression System: HEK293 Cells
IL-2RG Protein, Mouse, Recombinant (aa 25-263, hFc)
Cat.No: TMPJ-00239
Species: Mouse
Expression System: HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
Cat.No: TMPY-06036
Species: Human
Expression System: HEK293 Cells
HB-EGF Protein, Human, Recombinant
Cat.No: TMPY-02246
Species: Human
Expression System: Baculovirus Insect Cells
Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00828
Species: Human
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00392
Species: Human
Expression System: HEK293 Cells
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00394
Species: Human
Expression System: HEK293 Cells
IGFBP-7 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01371
Species: Human
Expression System: HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00395
Species: Human
Expression System: HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00393
Species: Human
Expression System: HEK293 Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
Cat.No: TMPY-06035
Species: Human
Expression System: HEK293 Cells
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